iFR Co-registration

Elevate your physiologic decision-making with iFR Co-registration

Only Philips iFR Co-registration helps you decide where to treat by mapping the iFR pull back directly onto the angiogram for a new dimension in PCI guidance.

Confident assessment: 38% of stenoses severity classifications changed when using iFR Co-registration compared to using angiography alone.^2,3
Minimize unnecessary stent placement: iFR Co-registration helps identify lesions that will truly benefit from PCI.
Tailored intervention: Obtain additional perspective on PCI planning by helping identify strategies for the most physiological gain.

Demonstrated results

1 in 4

patients with an angiographically successful PCI left the cath lab with residual ischemia (defined as iFR <0.90 residual DS <50% in any treated lesion).¹

81.6%

of patients with residual ischemia, were caused by an untreated angiographically inapparent physiologically focal stenosis (≤ 15 mm).¹

79%

reduction in residual ischemia if all focal lesions had been successfully treated (24% to 5%).¹

68%

relative reduction in clinical events at 1 year follow-up among patients achieving post-PCI iFR ≥ 0.95 (p-value=0.04).²

Features

Advanced physiologic guidance with Philips iFR

Virtually plan your PCI and predict results

Angiography provides a visual picture, but often lacks the detail needed for optimal PCI planning. Only Philips provides advanced physiologic guidance to help you determine not just whether to treat, but also where to treat, ensuring precise, patient-focused care.

Identify the precise locations causing ischemia - each yellow dot signifies a 0.01 drop of iFR
Plan your treatment, before a stent is even placed, with a virtual stent
Determine lesion lengths without need for a pullback device
Predict physiologic gain with iFR Estimate to determine the best treatment strategies

Get advanced physiologic insight

Quickly review pressure drops and precise ischemia locations so you can plan your treatment strategy more accurately and easily.
Automatically co-register values in seconds onto the angiogram to give you a complete picture.
Easily assess treatment strategy decisions with virtual stenting to ensure you achieve maximize physiologic gain and reduce guesswork.

Quickly and easily understand lesion-specific physiology

Quick iFR Co-registration graphically displays the iFR drop along the angiogram, highlighting which portion of the vessel is ischemic.

Make length measurements without a cumbersome pull back device

iFR Co-registration is calibrated for distance, so with a simple manual pullback you can make measurements on the angiogram and trend line.

iFR and IVUS Tri-registration

Obtain easy measurements that combine IVUS and iFR information with the angiogram to help determine if a stent will meet the procedural objectives.

World’s first solid core pressure guide wire.⁷

With an all new workhorse design, only Philips OmniWire pressure wire combines confidence in wire performance with proven outcomes and iFR Co-registration, making it easy to benefit from physiology throughout the case.^{1, 5-6}

View OmniWire

Philips iFR Co-registration technology is available on

IntraSight

The IntraSight Interventional Applications Workspace is where imaging, physiology, co-registration* and software all come together to help identify coronary and peripheral artery disease, and allow for more optimized treatment plans. IntraSight is built on a new foundational platform designed to meet the evolving needs of your lab today and tomorrow.

IGTDINTRSGHT

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SyncVision

The SyncVision precision guidance system is suitable with IntraSight and Core Integrated interventional platforms and streamlines lesion assessment, simplifies vessel sizing and enables precise therapy delivery all while integrating seamlessly in daily workflows in interventional suites of choice.

IGTDSYNC

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Documentation

Video assets: Case example: iFR Co-registration workflow

Improving PCI with iFR Co-registration

Transforming how we do PCI with iFR Co-registration

iFR Co-registration case 2 with Dr. Sen

Diffuse LAD leading to OMT with Dr. Sen

Cases aided by co-registration with Dr. Jeremias

3 vessel disease with Dr. Seto

iFR Co-registration cade with Dr. Sen

Multi-vessel disease with Dr. Seto

Osital LCX with Dr. Mathews

Distal LM and LAD with Dr. Hernandez

Footnotes

[1] Jeremias A, et al. Blinded Physiological Assessment of Residual Ischemia After Successful Angiographic Percutaneous Coronary Intervention: The DEFINE PCI Study. JACC Cardiovasc Interv. 2019;12(20):1991-2001.

[2] Patel M., et al. 1-Year outcomes of blinded physiological assessment of residual ischemia after successful PCI. JACC Cardiol Interv. 2022;15(1):52-61.

[3] Joseph T, Foley M, Al-Lamee R. Physiology and Intravascular Imaging Coregistration—Best of all Worlds? Intervent Cardiol Clin 2023;12:71–82.

[4] Matsuo A, Kasahara T, Ariyoshi M, et al. Utility of angiography–physiology coregistration maps during percutaneous coronary intervention in clinical practice. Cardiovasc Interv Ther 2021;36(2):208–18.
[5] Davies JE, et al., Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI. N Engl J Med. 2017 May 11;376(19):1824-1834.
[6] Gotberg M, et al., iFR-SWEDEHEART Investigators. Instantaneous Wave-free Ratio versus Fractional Flow Reserve to Guide PCI. N Engl J Med. 2017 May 11;376(19):1813-1823.
[7] Data on file D000410086_A, D000485394_A

Always read the label and follow the directions for use.

Philips medical devices should only be used by physicians and teams trained in interventional techniques, including training in the use of this device.

Products subject to country availability. Please contact your local sales representative.

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